Pdf overview of factors affecting oral drug absorption. You will primarily be tested on the definition and how various factors have an impact. With increase of the temperature they became less soluble in each other and in water, but more soluble in organic solvents. Factors affecting solubility solvent and types of solute, temperature, pressure and common ion effect are factors affecting solubility. Solubility and factors affecting solubility chemistry. Increase in temperature increases the solubility and viceversa. Choose from 500 different sets of factors affecting solubility flashcards on quizlet. Use this quiz and worksheet to see if you can answer that question. If the dissolution process is endothermic then the solubility should increase with an increase in temperature in accordance with le chateliers principle. The faster the water molecules are moving, the more collisions occur with the salt ions. Overview of factors affecting oral drug absorption naining song a,b, shaoy u zhang b, changxiao liu a a tianjin state key laboratory of pharmacokinetics and pharmaco dynamics, tianjin inst. Apart from the nature of solute and solvent, temperature also affects solid solubility considerably. An increase in pressure and an increase in temperature in this reaction results in greater solubility. The change in solubility cannot be determined from the given information.
Many salts show a large increase in solubility with temperature. In this video we learn about some of the factors that affect the solubility of solids and gases in water. Factors affecting solubility presentation2 free download as powerpoint presentation. Solution the reaction is exothermic, so an increase in temperature means that solubility would decrease. The 6 factors affecting solubility main life persona. The solubility of a given solute in a given solvent typically depends on temperature. Factors affecting solubility presentation2 solubility. Main factors affecting solubility are the polarity, the effect of the common ion, the temperature, the pressure, the nature of the solute and the mechanical factors. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
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